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Thymosin Alpha-1 (Tα1)

Immune-system peptide. Approved in many countries for hepatitis B/C and as adjunct to chemotherapy. Used here for chronic immune issues and post-illness recovery.

Immune
Evidence: Moderate

Thymosin Alpha-1 (Tα1): Immune-system peptide. Approved in many countries for hepatitis B/C and as adjunct to chemotherapy. Used here for chronic immune issues and post-illness recovery. Thymosin Alpha-1 is the immune-system peptide.

FDA ⓘ
Not approved
WADA
Not banned
Typical dose
1.6 mg sub-q
Half-life ⓘ
~2 hours
Route ⓘ
Subcutaneous
Schedule
1-2x weekly
In plain English

Thymosin Alpha-1 is the immune-system peptide. Approved in many countries for hepatitis and as adjunct to chemotherapy. Used here for chronic immune issues, post-illness recovery, or as a winter immune-support tool.

Status & legalityWhat do these mean? →
Natty? ⓘ
Not natty
FDA ⓘ
Not approved

Not FDA approved in the U.S. Has orphan drug status for some indications. Approved in 35+ countries (sold as Zadaxin) for hepatitis B/C and chemotherapy adjunct.

Compounding ⓘ
Category 1

Compounding pharmacies may prepare under physician prescription (post Feb 2026 reclassification, pending formal FDA publication).

WADA ⓘ
Not listed

Interpretation varies, falls outside explicit S2 listing.

Prescribed ⓘ

Yes outside the U.S., prescribed by hepatology / oncology providers in countries where Zadaxin is approved.

Who it's for

  • →Users with chronic immune issues
  • →Post-illness recovery support
  • →Cancer / hepatitis-adjunct context under medical care

What to expect

  1. Week 1

    Subtle. Energy / immune-feel often shifts first.

  2. Week 4

    Chronic-illness markers improve in clinical contexts.

  3. Week 8

    Plateau. Cycle off.

Looking at Thymosin Alpha-1 (Tα1)? Your next 3 steps

  1. 1Work out your syringe units

    Vial size + BAC water turns into the exact units to draw for Thymosin Alpha-1 (Tα1).

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  2. 2See what to stack & monitor

    The companion supplements and the bloodwork worth tracking on this kind of protocol.

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  3. 3Save it & ask the Coach

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How it works (mechanism)

28-amino-acid peptide derived from prothymosin alpha. Activates Toll-like receptors (both TLR2 and TLR9) on dendritic cells, broadly enhancing T-cell-mediated immune responses without direct antigen specificity.

Dosing protocol

Members only

Stacks well with

Members only

Side effects

01Generally well tolerated
02Mild injection-site irritation

When NOT to use

  • ⚠Active immunosuppression therapy (talk to provider)
  • ⚠Pregnancy / nursing

Bloodwork to monitor

  • • CBC if running long term

Common mistakes

  • • Treating it like an acute immune fix
  • • Skipping cycle breaks
  • • Underdosing for chronic conditions

Drug & supplement interactions

  • ⚠Immunosuppressants (cyclosporine, tacrolimus, biologics): may counteract Tα1's immune-enhancing effect
  • ⚠Vaccination: may enhance vaccine response
  • ⚠Limited published interaction data outside oncology / hepatitis contexts

Community patterns

Members only
Free, no account needed

New to Thymosin Alpha-1 (Tα1)? Grab the starter checklist.

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AI Coach, live sample
Members only
is 250mcg of bpc enough for a knee injury?
For a knee, 250 mcg sub-q daily is the standard working dose and a solid place to start. The trick with BPC is consistency, give it weeks, not days. Inject close to the joint, run it 4-6 weeks, and don't drop below 200 mcg, it tends to stop cracking the threshold reliably down there. If it hasn't moved at all by week 3, that's when adding TB-500 earns its place.
how much bac water for a 10mg reta vial?
3 mL is the standard play for a 10 mg reta vial. That's 3,333 mcg/mL, clean unit math across the titration: 2 mg = 60 units, 4 mg = 120 units, 6 mg = 180 units on a 100-unit insulin syringe. Run 2 mL instead if you want fewer, more concentrated shots (5,000 mcg/mL, so 2 mg = 40 units). Since most people titrate up over ~12 weeks, 3 mL keeps the numbers cleanest.
what should i track on bloodwork for tirzepatide?
Lipid panel, ALT/AST (liver enzymes), and an A1C, baseline before you start then every 3 months. If you've got metabolic-syndrome history, add fasting glucose and insulin so you can actually watch insulin sensitivity improve. You don't need a big hormone panel for a GLP-1.

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Frequently asked

What is Thymosin Alpha-1 (Tα1)?+
Thymosin Alpha-1 is the immune-system peptide. Approved in many countries for hepatitis and as adjunct to chemotherapy. Used here for chronic immune issues, post-illness recovery, or as a winter immune-support tool.
Is Thymosin Alpha-1 (Tα1) FDA approved?+
Not FDA approved in the U.S. Has orphan drug status for some indications. Approved in 35+ countries (sold as Zadaxin) for hepatitis B/C and chemotherapy adjunct.
Is Thymosin Alpha-1 (Tα1) legal?+
Thymosin Alpha-1 (Tα1) is not FDA-approved. It is sold by compounding pharmacies (with a prescription) and as "research only" by peptide vendors. Possession is generally not criminalized but distribution without authorization may be. Verify local laws.
Is Thymosin Alpha-1 (Tα1) banned by WADA?+
Thymosin Alpha-1 (Tα1) is not currently on the WADA prohibited list. Interpretation varies, falls outside explicit S2 listing.
Are you still natty after taking Thymosin Alpha-1 (Tα1)?+
No. Thymosin Alpha-1 (Tα1) is a performance-enhancing peptide and would disqualify a strict natty claim.
Do doctors prescribe Thymosin Alpha-1 (Tα1)?+
Yes outside the U.S., prescribed by hepatology / oncology providers in countries where Zadaxin is approved.
What's the typical dose of Thymosin Alpha-1 (Tα1)?+
Dosing depends on your goal, experience, and tolerance. The full Thymosin Alpha-1 (Tα1) protocol (dose, frequency, and how to titrate) is in the members section on the entry page.
What are the side effects of Thymosin Alpha-1 (Tα1)?+
Common side effects include: Generally well tolerated; Mild injection-site irritation. Less common effects and full safety details are on the entry page.
How long until Thymosin Alpha-1 (Tα1) starts working?+
Subtle. Energy / immune-feel often shifts first.
What can you stack with Thymosin Alpha-1 (Tα1)?+
Thymosin Alpha-1 (Tα1) is commonly combined with complementary compounds. The full stacking protocol (what to pair, dosing, and timing) is in the members section on the entry page.
Where do people get Thymosin Alpha-1 (Tα1)?+
Pepdex does not sell, ship, or recommend suppliers. Thymosin Alpha-1 (Tα1) is not FDA-approved; prescription versions require licensed clinical care, and "research only" markets carry real legal and quality risks. /coa explains how to verify a Certificate of Analysis and /guides/scam-vendor-spotting covers the red flags.
Thymosin Alpha-1 (Tα1) vs LL-37, which is better?+
Thymosin Alpha-1 vs LL-37: immune modulator vs direct antimicrobial peptide. Different jobs in the same system. Full head-to-head comparison: https://pepdex.co/compare/thymosin-alpha-1-vs-ll-37

Head-to-head with Thymosin Alpha-1 (Tα1)

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Thymosin Alpha-1 (Tα1) vs LL-37 →

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